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In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin (Zocor) and pravastatin (Pravachol) had the fewest side effects in this class of medications. They also found that lower doses produced fewer side effects in general. Can doctors prescribe for friends? If clinicians write informal prescriptions for friends or family, their supervising physicians may also suffer the consequences. It's often considered a professional courtesy to write a prescription for someone else who thinks they may need an antibiotic, a cream, or some other prescription. Can fenofibrate affect kidney function? Abstract. Fenofibrate is known to increase serum creatinine, but this effect is fully reversible, even after long-term treatment. This iatrogenic creatinine rise does not increase the risk of adverse renal outcomes or cardiovascular events. Can high triglycerides cause death? 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